219704-16-2
Chemical Structure
m,p-Dimethyl PPE
- CAS No.: 219704-16-2
- Formula:C16H26ClN
- Molecular Weight:267.84
IUPAC Name: 3-(3,4-dimethylphenyl)-1-propylpiperidine hydrochloride
InChIKey: FYCADJCOSUMNIA-UHFFFAOYSA-N
SMILES: CCCN(CCC1)CC1C2=CC=C(C)C(C)=C2.Cl
Biological Activity: m,p-Dimethyl PPE is a D4 dopamine receptor ligand. m,p-Dimethyl PPE promotes GDP/GTP exchange of the G protein α-subunit, dissociates the receptor-G protein complex, stabilizes the low-affinity receptor state, and inhibits adenylate cyclase activity. m,p-Dimethyl PPE inhibits Forskolin (HY-15371)-induced melatonin synthesis in retinal photoreceptor cells and reduces the efficacy of full agonists when used in combination. m,p-Dimethyl PPE can be used in studies related to attention-deficit hyperactivity disorder[1].
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m,p-Dimethyl PPE | m,p-Dimethyl PPE is a D4 dopamine receptor ligand. m,p-Dimethyl PPE promotes GDP/GTP exchange of the G protein α-subunit, dissociates the receptor-G protein complex, stabilizes the low-affinity receptor state, and inhibits adenylate cyclase activity. m,p-Dimethyl PPE inhibits Forskolin (HY-15371)-induced melatonin synthesis in retinal photoreceptor cells and reduces the efficacy of full agonists when used in combination. m,p-Dimethyl PPE can be used in studies related to attention-deficit hyperactivity disorder. | |||||||||||||||||||||
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