219705-77-8
219705-77-8
Chemical Structure
ATZ-1993
- CAS No.: 219705-77-8
- Formula:C28H28N4O4
- Molecular Weight:484.55
IUPAC Name: 1-(1-(3-ethoxyphenyl)propyl)-7-(pyrimidin-5-ylmethoxy)-4,5-dihydro-1H-benzo[g]indazole-3-carboxylic acid
InChIKey: GEVQMCFWDDZLMU-UHFFFAOYSA-N
SMILES: O=C(C1=NN(C(C2=CC=CC(OCC)=C2)CC)C3=C1CCC4=CC(OCC5=CN=CN=C5)=CC=C43)O
Biological Activity: ATZ-1993 is an orally active, nonpeptide endothelin receptor subtype Aand endothelin receptor subtype B antagonist with pKi values of 8.69, 7.20, respectively. ATZ-1993 has the potential for the research of intimal hyperplasia after balloon denudation of the carotid artery[1].
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ATZ-1993 | ATZ-1993 is an orally active, nonpeptide endothelin receptor subtype Aand endothelin receptor subtype B antagonist with pKi values of 8.69, 7.20, respectively. ATZ-1993 has the potential for the research of intimal hyperplasia after balloon denudation of the carotid artery. | |||||||||||||||||||||
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