22033-87-0
22033-87-0
Chemical Structure
Olesoxime
Synonym(s): TRO 19622; NSC 21311
- CAS No.: 22033-87-0
- Formula:C27H45NO
- Molecular Weight:399.65
IUPAC Name: (8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-((R)-6-methylheptan-2-yl)-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one oxime
InChIKey: QNTASHOAVRSLMD-GYKMGIIDSA-N
SMILES: C[C@@]12C(CC[C@]3([H])[C@]2([H])CC[C@@]4(C)[C@@]3([H])CC[C@@]4([C@]([H])(C)CCCC(C)C)[H])=CC(CC1)=NO
Biological Activity: Olesoxime (TRO 19622) is a mitochondrial-targeted neuroprotective compound with mean EC50 value for increasing cell survival is 3.2±0.2 μM.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Olesoxime | 99.04% | Olesoxime (TRO 19622) is a mitochondrial-targeted neuroprotective compound with mean EC50 value for increasing cell survival is 3.2±0.2 μM. | ||||||||||||||||||||
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Cholestenone (Standard) | 98.68% | Cholestenone (Standard) (4-Cholesten-3-one (Standard)) is the analytical standard of Cholestenone (HY-113365). This product is intended for research and analytical applications. Cholestenone (4-cholesten-3-one) is an orally available antimicrobial agent that is metabolized primarily in the liver as an intermediate oxidation product of cholesterol. Cholestenone inhibits human dermal fibroblast migration and fights Helicobacter pylori infection in vitro and in mouse models by inhibiting cholesterol-α-D-glucopyranoside (CGL). Cholestenone also alleviates metabolic disorders caused by obesity in db/db mice. | ||||||||||||||||||||
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Cholestenone-13C | 99.0% | Cholestenone-13C is the 13C labeled Cholestenone. Cholestenone (4-Cholesten-3-one), the intermediate oxidation product of cholesterol, is metabolized primarily in the liver. Cholestenone is highly mobile in membranes and influences cholesterol flip-flop and efflux. Cholestenone may cause long-term functional defects in cells. | ||||||||||||||||||||
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Cholestenone-13C2 | 99.06% | Cholestenone-13C2 is the 13C labeled Cholestenone. Cholestenone (4-Cholesten-3-one), the intermediate oxidation product of cholesterol, is metabolized primarily in the liver. Cholestenone is highly mobile in membranes and influences cholesterol flip-flop and efflux. Cholestenone may cause long-term functional defects in cells. | ||||||||||||||||||||
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Cholesterol (GMP Like, synthetic) | 99.89% | Cholesterol (GMP Like, synthetic) is Cholesterol (synthetic) (HY-N0322E) produced by using GMP like guidelines. GMP Like small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Cholesterol (synthetic) is a synthetic form of cholesterol. It is a lipid that sustains vital functions. Cholesterol (synthetic) can be used in research on cardiovascular diseases. | ||||||||||||||||||||
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Cholesterol-13C5 | 99.5% | Cholesterol-13C5 is the 13C-labeled Cholesterol. Cholesterol is the major sterol in mammals. It is making up 20-25% of structural component of the plasma membrane. Plasma membranes are highly permeable to water but relatively impermeable to ions and protons. Cholesterol plays an important role in determining the fluidity and permeability characteristics of the membrane as well as the function of both the transporters and signaling proteins. Cholesterol is also an endogenous estrogen-related receptor α (ERRα) agonist. | ||||||||||||||||||||
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Cholesterol-13C2 | 99.66% | Cholesterol-13C2 is the 13C labeled Cholesterol. Cholesterol is the major sterol in mammals. It is making up 20-25% of structural component of the plasma membrane. Plasma membranes are highly permeable to water but relatively impermeable to ions and protons. Cholesterol plays an important role in determining the fluidity and permeability characteristics of the membrane as well as the function of both the transporters and signaling proteins. Cholesterol is also an endogenous estrogen-related receptor α (ERRα) agonist. | ||||||||||||||||||||
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Cholesterol-18O | Cholesterol-18O is the 18O-labeled Cholesterol. Cholesterol is the major sterol in mammals. It is making up 20-25% of structural component of the plasma membrane. Plasma membranes are highly permeable to water but relatively impermeable to ions and protons. Cholesterol plays an important role in determining the fluidity and permeability characteristics of the membrane as well as the function of both the transporters and signaling proteins. Cholesterol is also an endogenous estrogen-related receptor α (ERRα) agonist. | |||||||||||||||||||||
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β-Sitostenone | 95.0% | β-Sitostenone (Δ4-Sitosterol-3-one; β-Rosasterol oxide) is a sterol isolated from Cleistanthus eberhardtii. β-Sitostenone inhibits tyrosinase (tyrosinase) and cyclooxygenase (COX-1 and COX-2). β-Sitostenone has potential anti-melanogenic, anticancer, and anti-inflammatory activities. β-Sitostenone can be used in research on inflammation, cancer, and cosmetics. | ||||||||||||||||||||
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Sitosterone | Sitosterone is a steroid that can be isolated from stem bark of syzygium aqueum. Sitosterone shows cytotoxicity. | |||||||||||||||||||||
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Cholesterylamine | 95.0% | Cholesterylamine is a cationic lipid and cholesterol analog. Cholesterylamine mimics the membrane transport properties of cholesterol, cycles between the plasma membrane and early/recycling endosomes in mammalian cells, and serves as a platform for constructing synthetic cell surface receptors. Cholesterylamine can be used to prepare PLGA particles with surface charges for antigen binding. Cholesterylamine is applicable for drug delivery. Cholesterylamine is used in research on autoimmune diseases and allergies. | ||||||||||||||||||||
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