2206744-61-6
Chemical Structure
SKI-73
- CAS No.: 2206744-61-6
- Formula:C46H58N8O8
- Molecular Weight:851.00
IUPAC Name: (2S,5S)-6-((2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)-5-((benzylamino)methyl)-N-(4-methoxyphenethyl)-2-(3-methyl-3-(2,4,5-trimethyl-3,6-dioxocyclohexa-1,4-dien-1-yl)butanamido)hexanamide
InChIKey: HZHUKQLWLNDVDZ-IBDVCRJISA-N
SMILES: O[C@H]1[C@@H](O)[C@H](N2C(N=CN=C3N)=C3N=C2)O[C@@H]1C[C@@H](CNCC4=CC=CC=C4)CC[C@@H](C(NCCC5=CC=C(OC)C=C5)=O)NC(CC(C)(C)C6=C(C)C(C(C)=C(C)C6=O)=O)=O
Biological Activity: SKI-73 is a chemical probe for CARM1 with prodrug properties. SKI-73 can rapidly penetrate cell membranes and be processed into active inhibitors. SKI-73 inhibits the invasion of breast cancer cells and can be used in the study of cancer[1].
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SKI-73 | SKI-73 is a chemical probe for CARM1 with prodrug properties. SKI-73 can rapidly penetrate cell membranes and be processed into active inhibitors. SKI-73 inhibits the invasion of breast cancer cells and can be used in the study of cancer. | |||||||||||||||||||||
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