2210247-59-7
2210247-59-7
Chemical Structure
Mal-amide-PEG8-Val-Ala-PAB-PNP
- CAS No.: 2210247-59-7
- Formula:C48H68N6O19
- Molecular Weight:1033.08
IUPAC Name: 4-((2S,5S)-37-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-5-isopropyl-2-methyl-4,7,35-trioxo-10,13,16,19,22,25,28,31-octaoxa-3,6,34-triazaheptatriacontanamido)benzyl (4-nitrophenyl) carbonate
InChIKey: XKNFUEHAHZGFPB-PXQFAMQDSA-N
SMILES: O=C(CCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCN1C(C=CC1=O)=O)=O)N[C@@H](C(C)C)C(N[C@@H](C)C(NC2=CC=C(C=C2)COC(OC3=CC=C(C=C3)[N+]([O-])=O)=O)=O)=O
Biological Activity: Mal-amide-PEG8-Val-Ala-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Mal-amide-PEG8-Val-Ala-PAB-PNP | 95.33% | Mal-amide-PEG8-Val-Ala-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). | ||||||||||||||||||||
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Mal-PEG2-VCP-NB | 98.25% | Mal-PEG2-VCP-NB is a claevable ADC linker containing a Maleimide group, 2-unit PEG and a VCP NB. | ||||||||||||||||||||
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MC-Val-Ala-PAB-PNP | 99.31% | MC-Val-Ala-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). | ||||||||||||||||||||
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Mal-PEG1-Val-Cit-PAB-PNP | 98.41% | Mal-PEG1-Val-Cit-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). | ||||||||||||||||||||
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Mal-PEG4-Val-Cit-PAB-PNP | 98.48% | Mal-PEG4-Val-Cit-PAB-PNP is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). | ||||||||||||||||||||
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Mal-amido-PEG2-Val-Cit-PAB-PNP | 98.40% | Mal-amido-PEG2-Val-Cit-PAB-PNP is a cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). | ||||||||||||||||||||
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Mal-amido-PEG8-val-gly-PAB-OH | Mal-amido-PEG8-val-gly-PAB-OH is a cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). | |||||||||||||||||||||
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Mal-amide-PEG8-Val-Cit-PAB-OH | Mal-amide-PEG8-Val-Cit-PAB-OH is a cleavable ADC linker featuring a maleimide, a hydrophilic PEG spacer, a Val-Cit dipeptide, and a PAB functional group. Maleimide is used to covalently bind free thiols on the cysteine residues of proteins. The Val-Cit dipeptide is cleaved by cellular proteases within the cell to allow for efficient payload delivery with the help of the PAB structure. | |||||||||||||||||||||
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Mal-PEG4-VCP-NB | Mal-PEG4-VCP-NB (Compound 17) is a degradable ADC linker containing a maleimide group, 4 PEG units and VCP NB. | |||||||||||||||||||||
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Mal-amide-PEG8-Val-Cit-PAB-PNP | 98.05% | Mal-amide-PEG8-Val-Cit-PAB-PNP is a cleavable ADC linker. Mal-amide-PEG8-Val-Cit-PAB-PNP consists of maleimide, a PEG spacer, Val-Cit dipeptide, PAB and PNP carbonate, and is applicable for the synthesis of ADCs. | ||||||||||||||||||||
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Mal-Amide-PEG4-Val-Cit-PAB-PNP | Mal-Amide-PEG4-Val-Cit-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). | |||||||||||||||||||||
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