2219323-96-1
2219323-96-1
Chemical Structure
mTOR inhibitor-2
- CAS No.: 2219323-96-1
- Formula:C23H21N7O
- Molecular Weight:411.46
IUPAC Name: 2-(4-(9-(6-aminopyridin-3-yl)-2-oxopyrazino[2,3-c]quinolin-1(2H)-yl)piperidin-1-yl)acetonitrile
InChIKey: PQEIMHBVHXTVNA-UHFFFAOYSA-N
SMILES: O=C(N1C2CCN(CC#N)CC2)C=NC3=C1C4=CC(C5=CN=C(N)C=C5)=CC=C4N=C3
Biological Activity: mTOR inhibitor-2 is a highlt potent, selective and oral mTOR inhibitor with an IC50 of 7 nM. mTOR inhibitor-2 inhibits cellular phosphorylation of mTORC1 (pS6 and p4E-BP1) and mTORC2 (pAKT (S473)) substrates[1].
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mTOR inhibitor-2 | mTOR inhibitor-2 is a highlt potent, selective and oral mTOR inhibitor with an IC50 of 7 nM. mTOR inhibitor-2 inhibits cellular phosphorylation of mTORC1 (pS6 and p4E-BP1) and mTORC2 (pAKT (S473)) substrates. | |||||||||||||||||||||
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