2221029-53-2
2221029-53-2
Chemical Structure
25-Methoxyalisol F
- CAS No.: 2221029-53-2
- Formula:C31H50O5
- Molecular Weight:502.73
InChIKey: SYVCHNCTAQDUIE-NWRBOSGGSA-N
SMILES: C[C@@]12[C@@]3([C@]([C@H](CC1=C4[C@](O[C@](C[C@H]4C)([H])[C@@H](O)C(C)(C)OC)([H])C2)O)([H])[C@@]5([C@@](C(C)(C(CC5)=O)C)([H])CC3)C)C
Biological Activity: 25-Methoxyalisol F is a regulator of NOX4 and phosphorylated Nrf2 with anti-pulmonary fibrosis activity. 25-Methoxyalisol F modulates the NOX4-Nrf2 signaling pathway, regulates the expression of NOX4 and p-Nrf2, and ameliorates TGF-β1-induced cellular damage. 25-Methoxyalisol F can be used in studies related to pulmonary fibrosis[1][2][3].
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25-Methoxyalisol F | 25-Methoxyalisol F is a regulator of NOX4 and phosphorylated Nrf2 with anti-pulmonary fibrosis activity. 25-Methoxyalisol F modulates the NOX4-Nrf2 signaling pathway, regulates the expression of NOX4 and p-Nrf2, and ameliorates TGF-β1-induced cellular damage. 25-Methoxyalisol F can be used in studies related to pulmonary fibrosis. | |||||||||||||||||||||
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References
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[1]. Zhu, Denghui, et al. Protostane Triterpenoids with Anti-Pulmonary Fibrosis Activities Through Nox4-Nrf2 Signaling Pathway Isolated from Alisma Orientale. Available at SSRN.
- [2]. Li HM, et al. Protostane-Type Triterpenoids from Alisma orientale. Chemistry & biodiversity. 2017 Dec;14(12). [Content Brief]
- [3]. Feng L, et al. Alisma genus: Phytochemical constituents, biosynthesis, and biological activities. Phytotherapy research : PTR. 2021 Apr;35(4):1872-1886. [Content Brief]
