2225868-19-7
Chemical Structure
123B9
- CAS No.: 2225868-19-7
- Formula:C58H82ClFN12O20
- Molecular Weight:1321.79
InChIKey: ZXZGKHQTGOWDLQ-PEGXCLLXSA-N
SMILES: O=C(N[C@@H](C)C(N[C@@H](CC1=CC=C(C=C1)O)C(N2[C@@H](CCC2)C(N[C@@H](CC(O)=O)C(N[C@@H](CO)C(N[C@@H](C(C)C)C(N3[C@@H](CCC3)C(N[C@@H](CCCC)C(N[C@@H](CCO)C(N[C@@H](CO)C(N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CO)NC(COC4=CC=C(C(Cl)=C4)F)=O
Biological Activity: 123B9, a tumor-homing agent, is a potent and selective EphA2 agonist with a Kd value of 4.0 μM. 123B9 selectively targets the EphA2 tyrosine kinase receptor ligand-binding domain. 123B9 does not appreciably inhibit the ligand binding domains of the most closely related EphA3 and EphA4 receptors[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
123B9 | 98.71% | 123B9, a tumor-homing agent, is a potent and selective EphA2 agonist with a Kd value of 4.0 μM. 123B9 selectively targets the EphA2 tyrosine kinase receptor ligand-binding domain. 123B9 does not appreciably inhibit the ligand binding domains of the most closely related EphA3 and EphA4 receptors. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
