2226614-88-4
2226614-88-4
Chemical Structure
NV-5440
- CAS No.: 2226614-88-4
- Formula:C31H36N6O3S
- Molecular Weight:572.73
IUPAC Name: 2-(4-(5-((4-(2-cyanophenyl)piperazin-1-yl)methyl)-2,4-dimethylbenzoyl)piperazin-1-yl)benzenesulfonamide
InChIKey: BREWSTIKWAQLCH-UHFFFAOYSA-N
SMILES: N#CC=1C=CC=CC1N2CCN(CC3=CC(C(=O)N4CCN(C=5C=CC=CC5S(=O)(=O)N)CC4)=C(C=C3C)C)CC2
Biological Activity: NV-5440 (Compound I-120) is an mTORC1 inhibitor and glucose transporter inhibitor. NV-5440 targets GLUT-1, -2, -3, and -4, and shows no activity against GLUT-5. NV-5440 inhibits glucose uptake[1][2].
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NV-5440 | NV-5440 (Compound I-120) is an mTORC1 inhibitor and glucose transporter inhibitor. NV-5440 targets GLUT-1, -2, -3, and -4, and shows no activity against GLUT-5. NV-5440 inhibits glucose uptake. | |||||||||||||||||||||
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