2227443-66-3
Chemical Structure
NaPi2b-IN-3
- CAS No.: 2227443-66-3
- Formula:C45H51N5O7
- Molecular Weight:773.92
IUPAC Name: 4-(3-(4-(2-(3-(((2-(3-carboxy-N-methylpropanamido)ethyl)(pentan-3-yl)amino)methyl)benzamido)-1H-indole-3-carboxamido)phenyl)propyl)benzoic acid
InChIKey: BLXYKSFKLCOMJD-UHFFFAOYSA-N
SMILES: CCC(N(CC1=CC(C(NC2=C(C3=C(N2)C=CC=C3)C(NC4=CC=C(C=C4)CCCC5=CC=C(C=C5)C(O)=O)=O)=O)=CC=C1)CCN(C(CCC(O)=O)=O)C)CC
Biological Activity: NaPi2b-IN-3 (compound 5) is a potent sodium-dependent transport protein 2b (SLC34A2, NaPi2b) inhibitor with IC50s of 71 nM and 28 nM for human NaPi2b and rat NaPi2b, respectively. NaPi2b-IN-3 can be used for researching hyperphosphatemia[1].
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NaPi2b-IN-3 | NaPi2b-IN-3 (compound 5) is a potent sodium-dependent transport protein 2b (SLC34A2, NaPi2b) inhibitor with IC50s of 71 nM and 28 nM for human NaPi2b and rat NaPi2b, respectively. NaPi2b-IN-3 can be used for researching hyperphosphatemia. | |||||||||||||||||||||
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