2229976-08-1
2229976-08-1
Chemical Structure
3-(7-Bromo-1-oxoisoindolin-2-yl)piperidine-2,6-dione
- CAS No.: 2229976-08-1
- Formula:C13H11BrN2O3
- Molecular Weight:323.15
IUPAC Name: 3-(7-bromo-1-oxoisoindolin-2-yl)piperidine-2,6-dione
InChIKey: LYWTUUBOXDYLNV-UHFFFAOYSA-N
SMILES: O=C(C(N(CC1=C2C(Br)=CC=C1)C2=O)CC3)NC3=O
Biological Activity: 3-(7-Bromo-1-oxoisoindolin-2-yl)piperidine-2,6-dione is a Lenalidomide analog that can be useful in PROTAC research.
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3-(7-Bromo-1-oxoisoindolin-2-yl)piperidine-2,6-dione | 98.99% | 3-(7-Bromo-1-oxoisoindolin-2-yl)piperidine-2,6-dione is a Lenalidomide analog that can be useful in PROTAC research. | ||||||||||||||||||||
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Lenalidomide-Br | 99.86% | Lenalidomide-Br (Compound 41) is an analog of cereblon (CRBN) ligand Lenalidomide for E3 ubiquitin ligase, and is used in the recruitment of CRBN protein. Lenalidomide-Br can be connected to the ligand for protein by a linker to form PROTACs, such as the PROTAC STAT3 degrader SD-36 (HY-129602). | ||||||||||||||||||||
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Thalidomide-4-Br | 99.58% | Thalidomide-4-Br (compound 53) is a compound with a bromodomain. Thalidomide-4-Br can be used in the research of inflammation, tumor and neurology. | ||||||||||||||||||||
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Lenalidomide-5-Br | 99.33% | Lenalidomide-5-Br is the Lenalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein. Lenalidomide-5-Br can be connected to the ligand for protein by a linker to form PROTAC. | ||||||||||||||||||||
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Desamino lenalidomide-7-F | ≥98.0% | Desamino lenalidomide-7-F is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. Desamino lenalidomide-7-F can be linked to a target protein ligand via a linker to form a PROTAC. | ||||||||||||||||||||
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3-(6-Bromo-1-oxoisoindolin-2-yl)piperidine-2,6-dione | 99.85% | 3-(6-Bromo-1-oxoisoindolin-2-yl)piperidine-2,6-dione is a Lenalidomide analog that can be useful in PROTAC research. | ||||||||||||||||||||
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(R)-Desamino lenalidomide-5-Br | 99.69% | (R)-Desamino lenalidomide-5-Br is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. (R)-Desamino lenalidomide-5-Br can be linked to a target protein ligand via a linker to form a PROTAC. | ||||||||||||||||||||
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3-(7-Amino-1-oxoisoindolin-2-yl)piperidine-2,6-dione | 99.09% | 3-(7-Amino-1-oxoisoindolin-2-yl)piperidine-2,6-dione is a Lenalidomide analog that can be useful in PROTAC research. | ||||||||||||||||||||
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Desamino lenalidomide-7-OH | 99.11% | Desamino lenalidomide-7-OH is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. Desamino lenalidomide-7-OH can be linked to a target protein ligand via a linker to form a PROTAC. | ||||||||||||||||||||
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Desamino lenalidomide-7-propyne | Desamino lenalidomide-7-propyne is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. Desamino lenalidomide-7-propyne can be linked to a target protein ligand via a linker to form a PROTAC. | |||||||||||||||||||||
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(3S)Lenalidomide-5-Br | 98.61% | (3S)Lenalidomide-5-Br is a ligand for E3 ubiquitinase. (3S)Lenalidomide-5-Br can be used to synthesize PROTAC Cbl-b-IN-1 (HY-159608). | ||||||||||||||||||||
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