2230520-62-2
Chemical Structure
β2AR/M-receptor agonist-1
- CAS No.: 2230520-62-2
- Formula:C43H56BrN3O7
- Molecular Weight:806.82
IUPAC Name: (S)-3-((R)-2-cyclopentyl-2-hydroxy-2-phenylethoxy)-1-(3-(4-(3-(((S)-2-hydroxy-2-(8-hydroxy-2-oxo-1,2-dihydroquinolin-5-yl)ethyl)amino)propoxy)phenoxy)propyl)quinuclidin-1-ium bromide
InChIKey: UPFGVSJDACTVRC-GWMCZDATSA-N
SMILES: O[C@@H](C1=C2C(NC(C=C2)=O)=C(C=C1)O)CNCCCOC(C=C3)=CC=C3OCCC[N+]45C[C@H](C(CC5)CC4)OC[C@@](C6CCCC6)(C7=CC=CC=C7)O.[Br-]
Biological Activity: β2AR/M-receptor agonist-1 (example 131) is a muscarinic antagonist and β2 adrenoceptor agonist (MABA). β2AR/M-receptor agonist-1 shows potency to β2 adrenoceptor with an EC50 value of 9.2 nM. β2AR/M-receptor agonist-1 also has potency to muscarinic receptor with a Ki value of 30.2 nM. β2AR/M-receptor agonist-1 shows MABA potency with an EC50 value of 4.0 nM[1].
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β2AR/M-receptor agonist-1 | β2AR/M-receptor agonist-1 (example 131) is a muscarinic antagonist and β2 adrenoceptor agonist (MABA). β2AR/M-receptor agonist-1 shows potency to β2 adrenoceptor with an EC50 value of 9.2 nM. β2AR/M-receptor agonist-1 also has potency to muscarinic receptor with a Ki value of 30.2 nM. β2AR/M-receptor agonist-1 shows MABA potency with an EC50 value of 4.0 nM. | |||||||||||||||||||||
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