2230581-03-8
Chemical Structure
NFE2L2 activator 3
- CAS No.: 2230581-03-8
- Formula:C29H33ClN4O5S2
- Molecular Weight:617.18
IUPAC Name: (S)-3-(5-chloro-4-(((R)-4-ethyl-1,1-dioxido-3,4-dihydro-2H-benzo[b][1,4,5]oxathiazepin-2-yl)methyl)thiophen-2-yl)-3-(1-ethyl-4-methyl-1H-benzo[d][1,2,3]triazol-5-yl)-2,2-dimethylpropanoic acid
InChIKey: JUOIJFQBEIZEMD-KBMIEXCESA-N
SMILES: [C@@H]([C@](C(O)=O)(C)C)(C=1C(C)=C2C(=CC1)N(CC)N=N2)C3=CC(CN4S(=O)(=O)C=5C(O[C@H](CC)C4)=CC=CC5)=C(Cl)S3
Biological Activity: NFE2L2 activator 3 (Compound 3) is a NFE2L2/NRF2 activator. NFE2L2 activator 3 specifically activates the NAD(P)H:quinone oxidoreductase (NQO1) enzyme, with its EC50 < 1 nM. NFE2L2 activator 3 can be used for research on respiratory system diseases such as chronic obstructive pulmonary disease[1].
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NFE2L2 activator 3 | NFE2L2 activator 3 (Compound 3) is a NFE2L2/NRF2 activator. NFE2L2 activator 3 specifically activates the NAD(P)H:quinone oxidoreductase (NQO1) enzyme, with its EC50 < 1 nM. NFE2L2 activator 3 can be used for research on respiratory system diseases such as chronic obstructive pulmonary disease. | |||||||||||||||||||||
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