2230747-62-1
2230747-62-1
Chemical Structure
BTX306
- CAS No.: 2230747-62-1
- Formula:C20H19ClN4O4S
- Molecular Weight:446.91
InChIKey: UIJJBTOFEJMPCM-UHFFFAOYSA-N
SMILES: CC1=CC=C(C=C1Cl)NC(NCC2=C3CN(C(C3=CS2)=O)C4CCC(NC4=O)=O)=O
Biological Activity: BTX306 is a cereblon-targeting molecular glue degrader. BTX306 reduces myeloma cell viability and induces apoptosis. BTX306 overcomes myeloma cell resistance to Lenalidomide (HY-A0003) or Bortezomib (HY-10227). BTX306 is active against primary myeloma cells, and shows efficacy in vivo. BTX306 can be used for myeloma research[1].
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BTX306 | BTX306 is a cereblon-targeting molecular glue degrader. BTX306 reduces myeloma cell viability and induces apoptosis. BTX306 overcomes myeloma cell resistance to Lenalidomide (HY-A0003) or Bortezomib (HY-10227). BTX306 is active against primary myeloma cells, and shows efficacy in vivo. BTX306 can be used for myeloma research. | |||||||||||||||||||||
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