2231079-74-4
2231079-74-4
Chemical Structure
NCT-505
- CAS No.: 2231079-74-4
- Formula:C27H28FN5O3S
- Molecular Weight:521.61
IUPAC Name: 1-(6-fluoro-3-(4-(methylsulfonyl)piperazine-1-carbonyl)quinolin-4-yl)-4-phenylpiperidine-4-carbonitrile
InChIKey: XMNLWOQHMQRHDV-UHFFFAOYSA-N
SMILES: N#CC1(C2=CC=CC=C2)CCN(C3=C(C(N4CCN(S(=O)(C)=O)CC4)=O)C=NC5=CC=C(F)C=C35)CC1
Biological Activity: NCT-505 is a potent and selective aldehyde dehydrogenase (ALDH1A1) inhibitor, with an IC50 of 7 nM, and weakly inhibits hALDH1A2, hALDH1A3, hALDH2, hALDH3A1 (IC50s, >57, 22.8, 20.1, >57 μM).
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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NCT-505 | 99.37% | NCT-505 is a potent and selective aldehyde dehydrogenase (ALDH1A1) inhibitor, with an IC50 of 7 nM, and weakly inhibits hALDH1A2, hALDH1A3, hALDH2, hALDH3A1 (IC50s, >57, 22.8, 20.1, >57 μM). | ||||||||||||||||||||
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