2231399-03-2
2231399-03-2
Chemical Structure
IMM-H012
- CAS No.: 2231399-03-2
- Formula:C26H25F2N5O5S
- Molecular Weight:557.57
InChIKey: FEHPMLVVSQNYOF-UHFFFAOYSA-N
SMILES: CC1=NC(N)=NC2=C1C=C(C3=CC(NS(C4=C(F)C=C(F)C=C4)(=O)=O)=C(OC)N=C3)C=C2OC5CCOCC5
Biological Activity: IMM-H012 is a specific PI3K inhibitor with an IC50 of 0.80 nM against PI3Kα. IMM-H012 combined with [177Lu]Lu-P4 shows synergistic antitumor effects against stomach cancer and lung cancer[1].
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IMM-H012 | IMM-H012 is a specific PI3K inhibitor with an IC50 of 0.80 nM against PI3Kα. IMM-H012 combined with [177Lu]Lu-P4 shows synergistic antitumor effects against stomach cancer and lung cancer. | |||||||||||||||||||||
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