2234271-86-2
2234271-86-2
Chemical Structure
JI130
- CAS No.: 2234271-86-2
- Formula:C23H24N2O3
- Molecular Weight:376.45
IUPAC Name: (E)-N-(2-(allyloxy)phenethyl)-3-(7-methoxy-1H-indol-3-yl)acrylamide
InChIKey: BNTYDBBGNPFECO-VAWYXSNFSA-N
SMILES: O=C(/C=C/C1=CNC2=C1C=CC=C2OC)NCCC3=CC=CC=C3OCC=C
Biological Activity: JI130 (JI051 derivative ) is a stabilizer for the Hes1-PHB2 interaction. JI130 inhibits the ability of Hes1 to repress transcription. JI130 significantly reduces the tumor growth in a murine pancreatic tumor model and has the potential for managing pancreatic cancer[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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JI130 | 98.5% | JI130 (JI051 derivative ) is a stabilizer for the Hes1-PHB2 interaction. JI130 inhibits the ability of Hes1 to repress transcription. JI130 significantly reduces the tumor growth in a murine pancreatic tumor model and has the potential for managing pancreatic cancer. | ||||||||||||||||||||
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