2234276-60-7
2234276-60-7
Chemical Structure
AP-C6
- CAS No.: 2234276-60-7
- Formula:C15H15N5O
- Molecular Weight:281.31
IUPAC Name: 2-((4-(4-(1H-imidazol-1-yl)phenyl)pyrimidin-2-yl)amino)ethan-1-ol
InChIKey: YUFMLHFNWVRCRN-UHFFFAOYSA-N
SMILES: OCCNC1=NC=CC(C2=CC=C(N3C=NC=C3)C=C2)=N1
Biological Activity: AP-C6 is a potent inhibitor of guanosine 3′,5′-cyclic monophosphate (cGMP)-dependent protein kinase II (cGKII) with a pIC50 of 6.5. AP-C6 concentration-dependently inhibits human cGKII activity in vitro. AP-C6 potentiate cAMP signaling by PDE inhibition[1].
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AP-C6 | AP-C6 is a potent inhibitor of guanosine 3′,5′-cyclic monophosphate (cGMP)-dependent protein kinase II (cGKII) with a pIC50 of 6.5. AP-C6 concentration-dependently inhibits human cGKII activity in vitro. AP-C6 potentiate cAMP signaling by PDE inhibition. | |||||||||||||||||||||
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