223537-11-9
223537-11-9
Chemical Structure
GGFG-Exatecan TFA
- CAS No.: 223537-11-9
- Formula:C41H41F4N7O10
- Molecular Weight:867.80
InChIKey: OGWHYRZQNBBYQF-XYGBRJDMSA-N
SMILES: NCC(NCC(N[C@@H](CC1=CC=CC=C1)C(NCC(N[C@@H]2C3=C4C(C(N5C4)=CC([C@](O)(C(OC6)=O)CC)=C6C5=O)=NC7=CC(F)=C(C)C(CC2)=C73)=O)=O)=O)=O.OC(C(F)(F)F)=O
Biological Activity: GGFG-Exatecan TFA is a synthetic intermediate for drug-linker conjugates used in antibody-drug conjugates (ADCs). GGFG-Exatecan TFA consists of a glycyl-glycyl-phenylalanyl-glycine (GGFG) tetrapeptide linker and a DNA topoisomerase I inhibitor Exatecan (HY-13631). GGFG-Exatecan TFA can be used for the study of cancer[1].
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GGFG-Exatecan TFA | GGFG-Exatecan TFA is a synthetic intermediate for drug-linker conjugates used in antibody-drug conjugates (ADCs). GGFG-Exatecan TFA consists of a glycyl-glycyl-phenylalanyl-glycine (GGFG) tetrapeptide linker and a DNA topoisomerase I inhibitor Exatecan (HY-13631). GGFG-Exatecan TFA can be used for the study of cancer. | |||||||||||||||||||||
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