2237925-62-9
2237925-62-9
Chemical Structure
DMA-135 hydrochloride
- CAS No.: 2237925-62-9
- Formula:C16H18ClN7O
- Molecular Weight:359.81
IUPAC Name: 3-amino-N-carbamimidoyl-5-(dimethylamino)-6-(phenylethynyl)pyrazine-2-carboxamide hydrochloride
InChIKey: RBMSZKWMVJWPEP-UHFFFAOYSA-N
SMILES: O=C(C1=NC(C#CC2=CC=CC=C2)=C(N(C)C)N=C1N)NC(N)=N.Cl
Biological Activity: DMA-135 hydrochloride inhibits enterovirus 71 (EV71) IRES-dependent translation and replication. DMA-135 hydrochloride binds to enterovirus 71 (EV71) SLII domain with moderately high affinity (KD= 520 nM). DMA-135 hydrochloride has no significant toxicity in cell-based studies[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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DMA-135 hydrochloride | 98.04% | DMA-135 hydrochloride inhibits enterovirus 71 (EV71) IRES-dependent translation and replication. DMA-135 hydrochloride binds to enterovirus 71 (EV71) SLII domain with moderately high affinity (KD= 520 nM). DMA-135 hydrochloride has no significant toxicity in cell-based studies. | ||||||||||||||||||||
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