2241017-37-6
Chemical Structure
Isonicotinaldehyde 2-pyridin
- CAS No.: 2241017-37-6
- Formula:C11H10N4
- Molecular Weight:198.22
IUPAC Name: (E)-2-(2-(pyridin-4-ylmethylene)hydrazinyl)pyridine
InChIKey: FDWJJPXBTJDKLS-NTEUORMPSA-N
SMILES: C1(/C=N/NC2=NC=CC=C2)=CC=NC=C1
Biological Activity: Isonicotinaldehyde 2-pyridin is an antileishmanial agent that is effective against the promastigotes of L. amazonensis and L. braziliensis. Isonicotinaldehyde 2-pyridin has no significant toxic effects on mouse macrophages. The biological activity of Isonicotinaldehyde 2-pyridin is closely related to increasing reactive oxygen species (ROS) and interfering with parasite mitochondrial function. Isonicotinaldehyde 2-pyridin showed its effects on L. amazonensis in preliminary studies on its pharmacological mechanism of action[1].
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Isonicotinaldehyde 2-pyridin | Isonicotinaldehyde 2-pyridin is an antileishmanial agent that is effective against the promastigotes of L. amazonensis and L. braziliensis. Isonicotinaldehyde 2-pyridin has no significant toxic effects on mouse macrophages. The biological activity of Isonicotinaldehyde 2-pyridin is closely related to increasing reactive oxygen species (ROS) and interfering with parasite mitochondrial function. Isonicotinaldehyde 2-pyridin showed its effects on L. amazonensis in preliminary studies on its pharmacological mechanism of action. | |||||||||||||||||||||
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