2241298-26-8
2241298-26-8
Chemical Structure
D-PheTrAP
- CAS No.: 2241298-26-8
- Formula:C15H18N3O6P
- Molecular Weight:367.29
SMILES: O=P(OCCC1=CN([C@H](CC2=CC=CC=C2)C(O)=O)N=N1)(O)C(C)=O
Biological Activity: D-PheTrAP is a bisubstrate analog inhibitor of 1-Deoxy-d-xylulose 5-phosphate synthase (DXPS). D-PheTrAP inhibits Escherichia coli DXPS (EcDXPS) and Pseudomonas aeruginosa DXPS (PaDXPS) with IC50 values of 0.52 μM, 2.1 μM, 2.4 μM, and 1.7 μM for wild-type (WT) EcDXPS, EcA426E, WT PaDXPS, and PaE431A, respectively[1].
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D-PheTrAP | D-PheTrAP is a bisubstrate analog inhibitor of 1-Deoxy-d-xylulose 5-phosphate synthase (DXPS). D-PheTrAP inhibits Escherichia coli DXPS (EcDXPS) and Pseudomonas aeruginosa DXPS (PaDXPS) with IC50 values of 0.52 μM, 2.1 μM, 2.4 μM, and 1.7 μM for wild-type (WT) EcDXPS, EcA426E, WT PaDXPS, and PaE431A, respectively. | |||||||||||||||||||||
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