2241489-43-8
Chemical Structure
E3 ligase Ligand 14
- CAS No.: 2241489-43-8
- Formula:C38H52N4O7
- Molecular Weight:676.84
IUPAC Name: tert-butyl ((S)-1-(((S)-1-cyclohexyl-2-((2S,4S)-4-(3-hydroxyphenoxy)-2-(((R)-1,2,3,4-tetrahydronaphthalen-1-yl)carbamoyl)pyrrolidin-1-yl)-2-oxoethyl)amino)-1-oxopropan-2-yl)(methyl)carbamate
InChIKey: ZAGJVXJUYODMFQ-QEXUPYAZSA-N
SMILES: O=C(N[C@@H]1CCCC2=C1C=CC=C2)[C@H]3N(C[C@H](C3)OC4=CC=CC(O)=C4)C([C@@H](NC([C@H](C)N(C(OC(C)(C)C)=O)C)=O)C5CCCCC5)=O
Biological Activity: E3 ligase Ligand 14 is a ligand for E3 ubiquitin ligase. E3 ligase Ligand 14 can be connected to the ligand for protein by a linker to form PROTACs. PROTACs are inducers of ubiquitination-mediated degradation of cancer-promoting proteins[1].
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E3 ligase Ligand 14 | E3 ligase Ligand 14 is a ligand for E3 ubiquitin ligase. E3 ligase Ligand 14 can be connected to the ligand for protein by a linker to form PROTACs. PROTACs are inducers of ubiquitination-mediated degradation of cancer-promoting proteins. | |||||||||||||||||||||
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