2241669-08-7
Chemical Structure
AUTAC2
- CAS No.: 2241669-08-7
- Formula:C61H81FN10O14S
- Molecular Weight:1229.42
IUPAC Name: (R)-1-(3-((R)-4-(((2-amino-9-(4-fluorobenzyl)-6-oxo-6,9-dihydro-1H-purin-8-yl)thio)methyl)-2,5,21-trioxo-10,13,16-trioxa-3,6,20-triazatetracosan-24-amido)phenyl)-3-(3,4-dimethoxyphenyl)propyl (S)-1-(3,3-dimethyl-2-oxopentanoyl)piperidine-2-carboxylate
InChIKey: PZCJWAJPLITJCB-YQZOKAAQSA-N
SMILES: O=C([C@@H](NC(C)=O)CSC1=NC2=C(N=C(N)NC2=O)N1CC3=CC=C(F)C=C3)NCCCOCCOCCOCCCNC(CCC(NC4=CC=CC([C@@H](CCC5=CC=C(OC)C(OC)=C5)OC([C@@H]6CCCCN6C(C(C(C)(CC)C)=O)=O)=O)=C4)=O)=O
Biological Activity: AUTAC2 is a FKBP12-targeting autophagy-mediated degrader (AUTAC). AUTAC2 contains an FBnG (p-Fluorobenzyl Guanine) and an SLF (c ligand of FKBP) moiety. SLF binds non-covalently to FKBP12[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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AUTAC2 | 95.04% | AUTAC2 is a FKBP12-targeting autophagy-mediated degrader (AUTAC). AUTAC2 contains an FBnG (p-Fluorobenzyl Guanine) and an SLF (c ligand of FKBP) moiety. SLF binds non-covalently to FKBP12. | ||||||||||||||||||||
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