2241669-84-9
Chemical Structure
FBnG-(Cys-acetamide)-CH2-PEG3-CH2-CH2-CH2-NH2
- CAS No.: 2241669-84-9
- Formula:C27H39FN8O6S
- Molecular Weight:622.71
IUPAC Name: (R)-2-acetamido-3-((2-amino-9-(4-fluorobenzyl)-6-oxo-6,9-dihydro-1H-purin-8-yl)thio)-N-(3-(2-(2-(3-aminopropoxy)ethoxy)ethoxy)propyl)propanamide
InChIKey: WASXVJZZPMVOOY-NRFANRHFSA-N
SMILES: NCCCOCCOCCOCCCNC([C@H](CSC1=NC2=C(N=C(N)NC2=O)N1CC3=CC=C(F)C=C3)NC(C)=O)=O
Biological Activity: FBnG-(Cys-acetamide)-CH2-PEG3-CH2-CH2-CH2-NH2 is a tag-linker conjugate of AUTAC4 (HY-134640) that incorporates a degradation tag FBnG (HY-W073762) and a glycol linker. AUTAC4 contains an p-fluorobenzylguanine (FBnG) and a phenylindole moiety, which can induce K63-linked polyubiquitination and degradation of mitochondria in HeLa cells[1].
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FBnG-(Cys-acetamide)-CH2-PEG3-CH2-CH2-CH2-NH2 | 95.56% | FBnG-(Cys-acetamide)-CH2-PEG3-CH2-CH2-CH2-NH2 is a tag-linker conjugate of AUTAC4 (HY-134640) that incorporates a degradation tag FBnG (HY-W073762) and a glycol linker. AUTAC4 contains an p-fluorobenzylguanine (FBnG) and a phenylindole moiety, which can induce K63-linked polyubiquitination and degradation of mitochondria in HeLa cells. | ||||||||||||||||||||
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