2242724-49-6
Chemical Structure
TRPV2-selective blocker 1
- CAS No.: 2242724-49-6
- Formula:C15H18OS2
- Molecular Weight:278.43
InChIKey: RCALJRZMLQRHLX-UHFFFAOYSA-N
SMILES: CC(CC(C)/C(C1=CC=CC=C1)=C2SCCS\2)=O
Biological Activity: TRPV2-selective blocker 1 is a TRPV2-selective blocker that inhibits calcium influx and ionic currents. TRPV2-selective blocker 1 exhibits an IC50 of 6.3 μM against rat TRPV2, and shows no activity against TRPV1, TRPV3 or TRPV4 channels. TRPV2-selective blocker 1 attenuates macrophage phagocytosis, LPS-induced macrophage migration, and calcium microdomains generated by peripheral TRPV2. TRPV2-selective blocker 1 is non-cytotoxic and can be used to investigate the function of TRPV2 during immune processes[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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TRPV2-selective blocker 1 | 99.68% | TRPV2-selective blocker 1 is a TRPV2-selective blocker that inhibits calcium influx and ionic currents. TRPV2-selective blocker 1 exhibits an IC50 of 6.3 μM against rat TRPV2, and shows no activity against TRPV1, TRPV3 or TRPV4 channels. TRPV2-selective blocker 1 attenuates macrophage phagocytosis, LPS-induced macrophage migration, and calcium microdomains generated by peripheral TRPV2. TRPV2-selective blocker 1 is non-cytotoxic and can be used to investigate the function of TRPV2 during immune processes. | ||||||||||||||||||||
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