2243701-11-1
2243701-11-1
Chemical Structure
Dyrk1A-IN-12
- CAS No.: 2243701-11-1
- Formula:C22H16FN3O2S
- Molecular Weight:405.44
SMILES: O=C(C1=CC(OC)=CC=C1F)NC2=CN=CC(C3=CC(C4=CC=CN=C4)=CS3)=C2
Biological Activity: Dyrk1A-IN-12 (compound S43) is a Dyrk (Dual specificity tyrosine phosphorylation regulated kinase 1A inhibitor. Dyrk1A-IN-12 inhibits Dyrk1A with a IC50 of 95 nM. Dyrk1A-IN-12 shows anti-EV-A71 activity with an EC50 of 4.4 μM, CC50 of 12.8 μM and SI of 2.9. Dyrk1A-IN-12 shows potent inhibition against herpes simplex virus (HSV)[1].
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Dyrk1A-IN-12 | Dyrk1A-IN-12 (compound S43) is a Dyrk (Dual specificity tyrosine phosphorylation regulated kinase 1A inhibitor. Dyrk1A-IN-12 inhibits Dyrk1A with a IC50 of 95 nM. Dyrk1A-IN-12 shows anti-EV-A71 activity with an EC50 of 4.4 μM, CC50 of 12.8 μM and SI of 2.9. Dyrk1A-IN-12 shows potent inhibition against herpes simplex virus (HSV). | |||||||||||||||||||||
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