2243974-80-1
Chemical Structure
Morpholino A phosphoramidite
- CAS No.: 2243974-80-1
- Formula:C47H53N8O6P
- Molecular Weight:856.95
IUPAC Name: N-(9-((2R,6S)-6-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((2-cyanoethoxy)(diisopropylamino)phosphanyl)morpholin-2-yl)-9H-purin-6-yl)benzamide
InChIKey: ZRWXOZTUFQZCLQ-VUNVOEFOSA-N
SMILES: CC(C)N(C(C)C)P(OCCC#N)N(C1)C[C@H](N2C3=NC=NC(NC(C4=CC=CC=C4)=O)=C3N=C2)O[C@@H]1COC(C5=CC=C(C=C5)OC)(C6=CC=CC=C6)C7=CC=C(C=C7)OC
Biological Activity: Morpholino A phosphoramidite is a specialized chemical building block used to synthesize Phosphorodiamidate Morpholino Oligomers (PMOs). Morpholino A phosphoramidite contains the adenine (A) nucleobase attached to a morpholine ring, fitted with a phosphoramidite group. PMOs are synthetic gene knockdown tools heavily used in developmental biology and targeted therapeutics to inhibit gene expression or alter RNA splicing[1].
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Morpholino A phosphoramidite | Morpholino A phosphoramidite is a specialized chemical building block used to synthesize Phosphorodiamidate Morpholino Oligomers (PMOs). Morpholino A phosphoramidite contains the adenine (A) nucleobase attached to a morpholine ring, fitted with a phosphoramidite group. PMOs are synthetic gene knockdown tools heavily used in developmental biology and targeted therapeutics to inhibit gene expression or alter RNA splicing. | |||||||||||||||||||||
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