2245880-46-8
2245880-46-8
Chemical Structure
Avibactam tomilopil
Synonym(s): ARX-1796; AV-006
- CAS No.: 2245880-46-8
- Formula:C14H23N3O8S
- Molecular Weight:393.41
IUPAC Name: ethyl 3-(((((1R,2S,5R)-2-carbamoyl-7-oxo-1,6-diazabicyclo[3.2.1]octan-6-yl)oxy)sulfonyl)oxy)-2,2-dimethylpropanoate
InChIKey: JHSLCXRZVJOZQZ-ZJUUUORDSA-N
SMILES: NC([C@H]1[N@@]2C(N([C@H](CC1)C2)OS(OCC(C)(C)C(OCC)=O)(=O)=O)=O)=O
Biological Activity: Avibactam tomilopil (ARX-1796, AV-006) is an orally active prodrug of Avibactam and a β-lactamase inhibitor. Avibactam tomilopil can be used in the study of diseases such as urinary tract infections[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Avibactam tomilopil | 99.44% | Avibactam tomilopil (ARX-1796, AV-006) is an orally active prodrug of Avibactam and a β-lactamase inhibitor. Avibactam tomilopil can be used in the study of diseases such as urinary tract infections. | ||||||||||||||||||||
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References
- [1]. Huband MD, et al. Determination of MIC Quality Control Ranges for Ceftibuten-Avibactam (Fixed 4 μg/mL), a Novel β-Lactam/β-Lactamase Inhibitor Combination. J Clin Microbiol. 2023 Jul 20;61(7):e0165722. [Content Brief]
- [2]. Veeraraghavan B, et al. Oral Antibiotics in Clinical Development for Community-Acquired Urinary Tract Infections. Infect Dis Ther. 2021;10(4):1815-1835. [Content Brief]
- [3]. Falcone M, et al. Spotlight on ceftazidime/avibactam: a new option for MDR Gram-negative infections. J Antimicrob Chemother. 2016;71(10):2713-2722. [Content Brief]
