2247544-03-0
2247544-03-0
Chemical Structure
WS-384
- CAS No.: 2247544-03-0
- Formula:C18H21BrClN9S2
- Molecular Weight:542.91
InChIKey: AGRQTIDPOXRYGL-UHFFFAOYSA-N
SMILES: BrC1=CC=C(CSC2=NN3C(SC4=NN=NN4CCN(C)C)=CC(C)=NC3=N2)C=C1.Cl
Biological Activity: WS-384 is a dual LSD1 and DCN1-UBC12 protein-protein interaction inhibitor with oral activity, with IC50 values of 338.79 nM and 14.81 nM, respectively. WS-384 possesses anticancer activity and can cause cell cycle arrest, DNA damage, and induce apoptosis. WS-384 can be used in the research of non-small cell lung cancer (NSCLC)[1].
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WS-384 | 98.23% | WS-384 is a dual LSD1 and DCN1-UBC12 protein-protein interaction inhibitor with oral activity, with IC50 values of 338.79 nM and 14.81 nM, respectively. WS-384 possesses anticancer activity and can cause cell cycle arrest, DNA damage, and induce apoptosis. WS-384 can be used in the research of non-small cell lung cancer (NSCLC). | ||||||||||||||||||||
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