2249005-28-3
2249005-28-3
Chemical Structure
Z3071585108
- CAS No.: 2249005-28-3
- Formula:C17H16N6
- Molecular Weight:304.35
InChIKey: JVVLSCNLUICXDH-UHFFFAOYSA-N
SMILES: N#CC(C=CN=N1)=C1N(C2)CCCC2C3=CNC4=NC=CC=C43
Biological Activity: Z3071585108 is a small molecule binder of the LAG-3 D1 domain with Kd values measured for the MST-TRIC channel and spectral shift detection of 59.2 and 56.1 μM respectively. Z3071585108 partially inhibits the binding of LAG-3 to MHCII, with an EC₅₀ of 42.9 μM. Z3071585108 can be used for the study of small molecule immunotherapies targeting LAG-3[1].
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Z3071585108 | Z3071585108 is a small molecule binder of the LAG-3 D1 domain with Kd values measured for the MST-TRIC channel and spectral shift detection of 59.2 and 56.1 μM respectively. Z3071585108 partially inhibits the binding of LAG-3 to MHCII, with an EC₅₀ of 42.9 μM. Z3071585108 can be used for the study of small molecule immunotherapies targeting LAG-3. | |||||||||||||||||||||
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