2249799-35-5
Chemical Structure
(3S,5R)-Fluvastatin-d6 sodium
Synonym(s): (3S,5R)-XU 62-320-d6
- CAS No.: 2249799-35-5
- Formula:C24H19D6FNNaO4
- Molecular Weight:439.48
IUPAC Name: sodium (3S,5R,E)-7-(3-(4-fluorophenyl)-1-(propan-2-yl-1,1,1,3,3,3-d6)-1H-indol-2-yl)-3,5-dihydroxyhept-6-enoate
InChIKey: ZGGHKIMDNBDHJB-WPPSXBOFSA-M
SMILES: FC1=CC=C(C2=C(/C=C/[C@H](O)C[C@H](O)CC(O[Na])=O)N(C(C([2H])([2H])[2H])C([2H])([2H])[2H])C3=C2C=CC=C3)C=C1
Biological Activity: (3S,5R)-Fluvastatin-d6 (sodium)?is the deuterium labeled (3S,5R)-Fluvastatin sodium. Fluvastatin is a first fully synthetic, competitive?HMG-CoA reductase?inhibitor with an IC50?of 8 nM. Fluvastatin protects vascular smooth muscle cells against oxidative stress through the Nrf2-dependent antioxidant pathway[1].
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(3S,5R)-Fluvastatin-d6 sodium | (3S,5R)-Fluvastatin-d6 (sodium)?is the deuterium labeled (3S,5R)-Fluvastatin sodium. Fluvastatin is a first fully synthetic, competitive?HMG-CoA reductase?inhibitor with an IC50?of 8 nM. Fluvastatin protects vascular smooth muscle cells against oxidative stress through the Nrf2-dependent antioxidant pathway. | |||||||||||||||||||||
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(3S,5R)-Fluvastatin sodium | 98.16% | (3S,5R)-Fluvastatin sodium ((3S,5R)-XU 62-320) is the (3S,5R)-enantiomer of Fluvastatin. Fluvastatin is a first fully synthetic, competitive HMG-CoA reductase inhibitor with an IC50 of 8 nM. Fluvastatin protects vascular smooth muscle cells against oxidative stress through the Nrf2-dependent antioxidant pathway. | ||||||||||||||||||||
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