2249944-99-6
Chemical Structure
PROTAC MDM2 Degrader-2
- CAS No.: 2249944-99-6
- Formula:C70H76Cl4N10O12
- Molecular Weight:1391.22
IUPAC Name: N,N'-((ethane-1,2-diylbis(oxy))bis(ethane-2,1-diyl))bis(2-(4-((4R,5S)-4,5-bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxyphenyl)-4,5-dihydro-1H-imidazole-1-carbonyl)-2-oxopiperazin-1-yl)acetamide)
InChIKey: WZLSSHVSGKCEKQ-AKOOKZATSA-N
SMILES: O=C(N1CC(N(CC(NCCOCCOCCNC(CN2C(CN(C(N3[C@@H](C4=CC=C(Cl)C=C4)[C@@H](C5=CC=C(Cl)C=C5)N=C3C6=C(C=C(OC)C=C6)OC(C)C)=O)CC2)=O)=O)=O)CC1)=O)N7[C@@H](C8=CC=C(Cl)C=C8)[C@@H](C9=CC=C(Cl)C=C9)N=C7C%10=C(C=C(OC)C=C%10)OC(C)C
Biological Activity: PROTAC MDM2 Degrader-2 is an MDM2 PROTAC degrader. PROTAC MDM2 Degrader-2 can induce the self-ubiquitination and degradation of MDM2, thereby upregulating the level of p53 protein. PROTAC MDM2 Degrader-2 has anti-tumor activity and can be used in the study of cancer[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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PROTAC MDM2 Degrader-2 | 95.01% | PROTAC MDM2 Degrader-2 is an MDM2 PROTAC degrader. PROTAC MDM2 Degrader-2 can induce the self-ubiquitination and degradation of MDM2, thereby upregulating the level of p53 protein. PROTAC MDM2 Degrader-2 has anti-tumor activity and can be used in the study of cancer. | ||||||||||||||||||||
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