2250437-45-5
Chemical Structure
H-(Gly)3-Lys(N3)-OH
- CAS No.: 2250437-45-5
- Formula:C12H21N7O5
- Molecular Weight:343.34
IUPAC Name: N6-diazo-N2-glycylglycylglycyl-L-lysine
InChIKey: OTAJJAGRBJWUDS-QMMMGPOBSA-N
SMILES: NCC(NCC(NCC(N[C@H](C(O)=O)CCCCN=[N+]=[N-])=O)=O)=O
Biological Activity: The azide function is widely used for coupling to alkyne-containing fragments via the renowned Click reaction. Polyglycine fragments containing up to 7 glycines are reported to bind to surfaces and have potential application in nanotechnology constructs: constructs of Gly7-NHCH2-fragment containing peptides bind on mica surface in aqueous solution[1][2]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
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H-(Gly)3-Lys(N3)-OH | The azide function is widely used for coupling to alkyne-containing fragments via the renowned Click reaction. Polyglycine fragments containing up to 7 glycines are reported to bind to surfaces and have potential application in nanotechnology constructs: constructs of Gly7-NHCH2-fragment containing peptides bind on mica surface in aqueous solution. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups. | |||||||||||||||||||||
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