2253167-09-6
Chemical Structure
MM-589 TFA
- CAS No.: 2253167-09-6
- Formula:C30H45F3N8O7
- Molecular Weight:686.72
IUPAC Name: N-((3R,6S,9S,12R)-6-ethyl-12-methyl-9-(3-(3-methylguanidino)propyl)-2,5,8,11-tetraoxo-3-phenyl-1,4,7,10-tetraazacyclotetradecan-12-yl)isobutyramide 2,2,2-trifluoroacetate
InChIKey: NARXNZHWAWPJIY-HTCBAMNXSA-N
SMILES: O=C(NCC[C@](NC(C(C)C)=O)(C)C1=O)[C@H](NC([C@@H](NC([C@H](CCCNC(NC)=N)N1)=O)CC)=O)C2=CC=CC=C2.FC(C(O)=O)(F)F
Biological Activity: MM-589 TFA is a potent inhibitor of WD repeat domain 5 (WDR5) and mixed lineage leukemia (MLL) protein-protein interaction. MM-589 binds to WDR5 with an IC50 of 0.90 nM and inhibits the MLL H3K4 methyltransferase activity with an IC50 of 12.7 nM[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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MM-589 TFA | 98.67% | MM-589 TFA is a potent inhibitor of WD repeat domain 5 (WDR5) and mixed lineage leukemia (MLL) protein-protein interaction. MM-589 binds to WDR5 with an IC50 of 0.90 nM and inhibits the MLL H3K4 methyltransferase activity with an IC50 of 12.7 nM. | ||||||||||||||||||||
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