2253996-66-4
2253996-66-4
Chemical Structure
Antiparasitic agent-4
- CAS No.: 2253996-66-4
- Formula:C16H13N3O2
- Molecular Weight:279.29
IUPAC Name: 2-(3-phenyl-1,2,4-oxadiazol-5-yl)-1-(pyridin-3-yl)prop-2-en-1-ol
InChIKey: DIWIKSHBGLXAEL-UHFFFAOYSA-N
SMILES: OC(C(C1=NC(C2=CC=CC=C2)=NO1)=C)C3=CC=CN=C3
Biological Activity: Antiparasitic agent-4 (compound 4q) has highly antiparasitic activity against Leishmania infantum (L. infantum) and Trypanosoma cruzi (T. cruzi) with IC50s of 8.51 μM and 2.20 μM, respectively. Antiparasitic agent-4 also has certain cytotoxicity against HepG2 (CC50 = 18.97 μM)[1].
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Antiparasitic agent-4 | Antiparasitic agent-4 (compound 4q) has highly antiparasitic activity against Leishmania infantum (L. infantum) and Trypanosoma cruzi (T. cruzi) with IC50s of 8.51 μM and 2.20 μM, respectively. Antiparasitic agent-4 also has certain cytotoxicity against HepG2 (CC50 = 18.97 μM). | |||||||||||||||||||||
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