2256087-35-9
2256087-35-9
Chemical Structure
CL4H6
- CAS No.: 2256087-35-9
- Formula:C59H113NO5
- Molecular Weight:916.53
IUPAC Name: 7-(4-(dipropylamino)butyl)-7-hydroxytridecane-1,13-diyl dioleate
InChIKey: ZFFZMGJMZGAGMF-SXAUZNKPSA-N
SMILES: CCCN(CCC)CCCCC(CCCCCCOC(CCCCCCC/C=C\CCCCCCCC)=O)(O)CCCCCCOC(CCCCCCC/C=C\CCCCCCCC)=O
Biological Activity: CL4H6 is a pH-sensitive cationic lipid. CL4H6 is the main component of lipid nanoparticles (LNPs), which can be used to target and deliver siRNA, and induces a potent gene-silencing response[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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CL4H6 | 98.32% | CL4H6 is a pH-sensitive cationic lipid. CL4H6 is the main component of lipid nanoparticles (LNPs), which can be used to target and deliver siRNA, and induces a potent gene-silencing response. | ||||||||||||||||||||
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References
- [1]. Amisha Sanghani, et al. Novel PEGylated Lipid Nanoparticles Have a High Encapsulation Efficiency and Effectively Deliver MRTF-B siRNA in Conjunctival Fibroblasts. Pharmaceutics. 2021 Mar 13;13(3):382. [Content Brief]
- [2]. Nour Shobaki, et al. Manipulating the function of tumor-associated macrophages by siRNA-loaded lipid nanoparticles for cancer immunotherapy. J Control Release. 2020 Sep 10;325:235-248. [Content Brief]
