2259318-51-7
Chemical Structure
Mal-Phe-C4-VC-PAB-MMAE
- CAS No.: 2259318-51-7
- Formula:C72H105N11O15
- Molecular Weight:1364.67
IUPAC Name: 4-((S)-2-((S)-2-(4-(4-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)phenyl)butanamido)-3-methylbutanamido)-5-ureidopentanamido)benzyl ((S)-1-(((S)-1-(((3R,4S,5S)-1-((S)-2-((1R,2R)-3-(((1S,2R)-1-hydroxy-1-phenylpropan-2-yl)amino)-1-methoxy-2-methyl-3-oxopropyl)pyrrolidin-1-yl)-3-methoxy-5-methyl-1-oxoheptan-4-yl)(methyl)amino)-3-methyl-1-oxobutan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)(methyl)carbamate
InChIKey: NGSQUXLVAHZKMZ-CZNGMLIJSA-N
SMILES: O[C@@H](C1=CC=CC=C1)[C@@H](C)NC([C@H](C)[C@H]([C@@]2([H])N(CCC2)C(C[C@@H](OC)[C@@]([C@@H](C)CC)([H])N(C)C([C@H](C(C)C)NC([C@H](C(C)C)N(C)C(OCC3=CC=C(NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCCC4=CC=C(N5C(C=CC5=O)=O)C=C4)=O)=O)=O)C=C3)=O)=O)=O)=O)OC)=O
Biological Activity: Mal-Phe-C4-VC-PAB-MMAE is a drug-linker conjugate for ADC composed of MMAE conjugated to the Mal-Phe-C4-VC-PAB linker. Mal-Phe-C4-VC-PAB-MMAE can be used to synthesize ROR1-targeting antibody-drug conjugates (ADCs) for research on ROR1-expressing cancers[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Mal-Phe-C4-VC-PAB-MMAE | 99.54% | Mal-Phe-C4-VC-PAB-MMAE is a drug-linker conjugate for ADC composed of MMAE conjugated to the Mal-Phe-C4-VC-PAB linker. Mal-Phe-C4-VC-PAB-MMAE can be used to synthesize ROR1-targeting antibody-drug conjugates (ADCs) for research on ROR1-expressing cancers. | ||||||||||||||||||||
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