2267329-76-8
Chemical Structure
TQB-3804
- CAS No.: 2267329-76-8
- Formula:C32H41BrN9O2P
- Molecular Weight:694.60
IUPAC Name: (6-((5-bromo-2-((2-methoxy-5-methyl-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)phenyl)amino)pyrimidin-4-yl)amino)quinoxalin-5-yl)dimethylphosphine oxide
InChIKey: ZYSKXRAGBGLELB-UHFFFAOYSA-N
SMILES: CN1CCN(C2CCN(C3=C(C)C=C(NC4=NC=C(Br)C(NC5=CC=C6N=CC=NC6=C5P(C)(C)=O)=N4)C(OC)=C3)CC2)CC1
Biological Activity: TQB-3804 is a potent, selective and orally active EGFR kinase inhibitor. TQB-3804 has inhibitory effect for for EGFR (WT) and EGFR (mutant C797S/T790M/L858R) with IC50 values of 7.92 nM and 0.218 nM, respectively. TQB-3804 can be used for the research of various cancers[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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TQB-3804 | 99.59% | TQB-3804 is a potent, selective and orally active EGFR kinase inhibitor. TQB-3804 has inhibitory effect for for EGFR (WT) and EGFR (mutant C797S/T790M/L858R) with IC50 values of 7.92 nM and 0.218 nM, respectively. TQB-3804 can be used for the research of various cancers. | ||||||||||||||||||||
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