22688-78-4
Chemical Structure
Kaempferol 3-O-β-D-glucuronide
Synonym(s): Kaempferol-3-glucuronide; Kaempferol-3-O-glucuronide
- CAS No.: 22688-78-4
- Formula:C21H18O12
- Molecular Weight:462.36
IUPAC Name: (2S,3S,4S,5R,6S)-6-((5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-3-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid
InChIKey: FNTJVYCFNVUBOL-ZUGPOPFOSA-N
SMILES: O[C@H]([C@H]([C@@H]([C@@H](C(O)=O)O1)O)O)[C@@H]1OC2=C(C3=CC=C(O)C=C3)OC4=CC(O)=CC(O)=C4C2=O
Biological Activity: Kaempferol 3-O-β-D-glucuronide (Kaempferol-3-glucuronide) is a metabolite of kaempferol that can be taken orally and has anti-inflammatory properties. Kaempferol 3-O-β-D-glucuronide can activate AKT/GSK3β phosphorylation and improve glucose metabolism[1][2][3].
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Kaempferol 3-O-β-D-glucuronide | 99.47% | Kaempferol 3-O-β-D-glucuronide (Kaempferol-3-glucuronide) is a metabolite of kaempferol that can be taken orally and has anti-inflammatory properties. Kaempferol 3-O-β-D-glucuronide can activate AKT/GSK3β phosphorylation and improve glucose metabolism. | ||||||||||||||||||||
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Kaempferol 3-O-β-D-glucuronide (Standard) | ≥98% | Kaempferol 3-O-β-D-glucuronide (Standard) (Kaempferol-3-glucuronide (Standard)) is the analytical standard of Kaempferol 3-O-β-D-glucuronide (HY-N7176). This product is intended for research and analytical applications. Kaempferol 3-O-β-D-glucuronide (Kaempferol-3-glucuronide) is a metabolite of kaempferol that can be taken orally and has anti-inflammatory properties. Kaempferol 3-O-β-D-glucuronide can activate AKT/GSK3β phosphorylation and improve glucose metabolism. | ||||||||||||||||||||
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References
- [1]. Khajuria V, et al. Kaempferol-3-o-β-d-glucuronate exhibit potential anti-inflammatory effect in LPS stimulated RAW 264.7 cells and mice model. Int Immunopharmacol. 2018;57:62-71. [Content Brief]
- [2]. Rupayan Bhattacharjee, et al. Extraction and Characterization of Flavonoid Kaempferol-3-Glucuronide from Mango for Treatment of Different Types of Cancers. Great Britain Journals Press. Print ISSN: 2631-8490
- [3]. Ge Fang, et al. The glucuronide metabolites of kaempferol and quercetin, targeting to the AKT PH domain, activate AKT/GSK3β signaling pathway and improve glucose metabolism. Journal of Functional Foods. Volume 82, July 2021, 104501.
