2270875-79-9
2270875-79-9
Chemical Structure
SMARCA2/4-IN-4
- CAS No.: 2270875-79-9
- Formula:C10H8ClF2N5OS
- Molecular Weight:319.72
InChIKey: BHNVQLOUIWHYIX-UHFFFAOYSA-N
SMILES: O=C(NC1=CC(C(F)F)=NS1)NC2=CC(Cl)=NC=C2N
Biological Activity: SMARCA2/4-IN-4 is a SMARCA2 and SMARCA4 inhibitor, with an IC50 value of <0.005 μM for both SMARCA2 and SMARCA4. SMARCA2/4-IN-4 exerts anticancer activity against BRG1-mutant melanoma. SMARCA2/4-IN-4 can be used for research related to Brg1/Smarca4-mutant cancers[1].
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SMARCA2/4-IN-4 | SMARCA2/4-IN-4 is a SMARCA2 and SMARCA4 inhibitor, with an IC50 value of <0.005 μM for both SMARCA2 and SMARCA4. SMARCA2/4-IN-4 exerts anticancer activity against BRG1-mutant melanoma. SMARCA2/4-IN-4 can be used for research related to Brg1/Smarca4-mutant cancers. | |||||||||||||||||||||
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