2271394-34-2
Chemical Structure
NVP-DFV890
Synonym(s): NLRP3 antagonist 2
- CAS No.: 2271394-34-2
- Formula:C19H24N4O3S2
- Molecular Weight:420.55
InChIKey: LHVWNNYPUDZLSH-MUUNZHRXSA-N
SMILES: O=C(N[S@](=N)(C(S1)=CN=C1C(C)(O)C)=O)NC2=C(CCC3)C3=CC4=C2CCC4
Biological Activity: NVP-DFV890 is an orally administered, selective NLRP3 inhibitor. NVP-DFV890 directly binds to NLRP3, blocks maturation of pro-inflammatory cytokines IL-1β and IL-18, and inhibits pyroptotic cell death. NVP-DFV890 acts as an inducer of viral clearance, promoting earlier clearance of SARS-CoV-2. NVP-DFV890 can be used for the research of COVID-19 pneumonia and coronavirus-associated acute respiratory distress syndrome (CARDS)[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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NVP-DFV890 | 99.97% | NVP-DFV890 is an orally administered, selective NLRP3 inhibitor. NVP-DFV890 directly binds to NLRP3, blocks maturation of pro-inflammatory cytokines IL-1β and IL-18, and inhibits pyroptotic cell death. NVP-DFV890 acts as an inducer of viral clearance, promoting earlier clearance of SARS-CoV-2. NVP-DFV890 can be used for the research of COVID-19 pneumonia and coronavirus-associated acute respiratory distress syndrome (CARDS). | ||||||||||||||||||||
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