227803-63-6
227803-63-6
Chemical Structure
Aclerastide
Synonym(s): DSC-127; NorLeu3-A(1-7)
- CAS No.: 227803-63-6
- Formula:C42H64N12O11
- Molecular Weight:913.03
InChIKey: RUBMHAHMIJSMHA-LBWFYSSPSA-N
SMILES: OC(C=C1)=CC=C1C[C@H](NC([C@H](CCCC)NC([C@H](CCCNC(N)=N)NC([C@@H](N)CC(O)=O)=O)=O)=O)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC2=CN=CN2)C(N3[C@@H](CCC3)C(O)=O)=O)=O)=O
Biological Activity: Aclerastide (DSC-127) is an angiotensin receptor agonist. Aclerastide also is a peptide analog of angiotensin II. Aclerastide can be used for the research of tissue regeneration in diabetic ulcers[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Aclerastide | 99.62% | Aclerastide (DSC-127) is an angiotensin receptor agonist. Aclerastide also is a peptide analog of angiotensin II. Aclerastide can be used for the research of tissue regeneration in diabetic ulcers. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
- [1]. Kathleen E Rodgers, et al. Acceleration of healing, reduction of fibrotic scar, and normalization of tissue architecture by an angiotensin analogue, NorLeu3-A(1-7). Plast Reconstr Surg. 2003 Mar;111(3):1195-206. [Content Brief]
- [2]. Trung T Nguyen, et al. Expression of active matrix metalloproteinase-9 as a likely contributor to the clinical failure of aclerastide in treatment of diabetic foot ulcers. Eur J Pharmacol. 2018 Sep 5;834:77-83. [Content Brief]
