2278276-46-1
2278276-46-1
Chemical Structure
Apitegromab
Synonym(s): SRK-015
- CAS No.: 2278276-46-1
- Formula:N/A
- Molecular Weight:(145.06 kDa)
SMILES: [Apitegromab]
Biological Activity: Apitegromab (SRK-015) is an anti-promyostatin monoclonal antibody. Apitegromab can be used for the research of neuromuscular disease including spinal muscular atrophy[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Apitegromab | 99.51% | Apitegromab (SRK-015) is an anti-promyostatin monoclonal antibody. Apitegromab can be used for the research of neuromuscular disease including spinal muscular atrophy. | ||||||||||||||||||||
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References
- [1]. Doreen Barrett, et al. A Randomized Phase 1 Safety, Pharmacokinetic and Pharmacodynamic Study of the Novel Myostatin Inhibitor Apitegromab (SRK-015): A Potential Treatment for Spinal Muscular Atrophy. Adv Ther. 2021 Jun;38(6):3203-3222. [Content Brief]
- [2]. Welsh BT, et al. Preclinical Safety Assessment and Toxicokinetics of Apitegromab, an Antibody Targeting Proforms of Myostatin for the Treatment of Muscle-Atrophying Disease. Int J Toxicol. 2021 Jul-Aug;40(4):322-336. [Content Brief]
