228418-82-4
Chemical Structure
LY-426965
- CAS No.: 228418-82-4
- Formula:C28H38N2O2
- Molecular Weight:434.61
IUPAC Name: (S)-1-cyclohexyl-4-(4-(2-methoxyphenyl)piperazin-1-yl)-2-methyl-2-phenylbutan-1-one
InChIKey: GXVHRYDXBSTHCF-NDEPHWFRSA-N
SMILES: O=C([C@@](C)(CCN1CCN(CC1)C2=CC=CC=C2OC)C3=CC=CC=C3)C4CCCCC4
Biological Activity: LY426965 is a potent arylpiperazine compound known for its role as a full antagonist of the serotonin 1A receptor, lacking partial agonist activity. It is identified as a selective 5-HT1A antagonist, showing promise in preclinical studies for treating conditions associated with serotonin dysregulation, such as smoking cessation and depression-related disorders[1].
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LY-426965 | LY426965 is a potent arylpiperazine compound known for its role as a full antagonist of the serotonin 1A receptor, lacking partial agonist activity. It is identified as a selective 5-HT1A antagonist, showing promise in preclinical studies for treating conditions associated with serotonin dysregulation, such as smoking cessation and depression-related disorders. | |||||||||||||||||||||
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