2299200-91-0
Chemical Structure
P2Y12 antagonist 2
- CAS No.: 2299200-91-0
- Formula:C23H24N4O5S
- Molecular Weight:468.53
IUPAC Name: 1-(3-cyano-5-oxo-5,7-dihydrofuro[3,4-b]pyridin-2-yl)-4-methyl-N-((4-methylbenzyl)sulfonyl)piperidine-4-carboxamide
InChIKey: UDMPNYKEHCRGIV-UHFFFAOYSA-N
SMILES: O=C(OC1)C2=C1N=C(N3CCC(C(NS(CC4=CC=C(C)C=C4)(=O)=O)=O)(C)CC3)C(C#N)=C2
Biological Activity: P2Y12 antagonist 2 is a potent P2Y12 receptor antagonist. P2Y12 antagonist 2 exhibits excellent antiplatelet aggregation potency with an IC50 value of 2.94 μM as well as antithrombotic efficacy in a rat ferric chloride model. P2Y12 antagonist 2 shows a superior safety profile than Clopidogrel (HY-15283) in a rat tail-bleeding model. P2Y12 antagonist 2 can be used to research thromboembolic disorders[1].
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P2Y12 antagonist 2 | P2Y12 antagonist 2 is a potent P2Y12 receptor antagonist. P2Y12 antagonist 2 exhibits excellent antiplatelet aggregation potency with an IC50 value of 2.94 μM as well as antithrombotic efficacy in a rat ferric chloride model. P2Y12 antagonist 2 shows a superior safety profile than Clopidogrel (HY-15283) in a rat tail-bleeding model. P2Y12 antagonist 2 can be used to research thromboembolic disorders. | |||||||||||||||||||||
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