2300967-40-0
2300967-40-0
Chemical Structure
KRAS G12C inhibitor 61
- CAS No.: 2300967-40-0
- Formula:C31H33ClFN7O2
- Molecular Weight:590.09
InChIKey: HBHOIHAXRLHFTR-MOPGFXCFSA-N
SMILES: O=C1N=C(N2[C@@H](C)CN([C@H](C)C2)C(C=C)=O)C3=C(N1C4=C(C)C=CN=C4C(C)C)N=C(C5=C(N)C=CC=C5F)C(Cl)=C3
Biological Activity: KRAS G12C inhibitor 61 (Example 3) inhibits phospho-ERK 1/2 in MIA PaCa-2 cells with an IC50 value of 9 nM. KRAS G12C inhibitor 61 can be used for research of pancreatic, colorectal, and lung cancers[1].
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KRAS G12C inhibitor 61 | KRAS G12C inhibitor 61 (Example 3) inhibits phospho-ERK 1/2 in MIA PaCa-2 cells with an IC50 value of 9 nM. KRAS G12C inhibitor 61 can be used for research of pancreatic, colorectal, and lung cancers. | |||||||||||||||||||||
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