2304448-00-6
2304448-00-6
Chemical Structure
Antibacterial agent 124
- CAS No.: 2304448-00-6
- Formula:C16H17ClFN3O2
- Molecular Weight:337.78
IUPAC Name: (S)-7-chloro-6-fluoro-3-(2-oxo-3-(piperidin-2-yl)propyl)quinazolin-4(3H)-one
InChIKey: LZMOBHASNVDDQN-JTQLQIEISA-N
SMILES: O=C(CN1C=NC2=CC(Cl)=C(C=C2C1=O)F)C[C@@H]3CCCCN3
Biological Activity: Antibacterial agent 124 (Compound 3) is a potent bacterial prolyl-tRNA synthetase (ProRS) inhibitor with an IC50 of 0.18 μM against Staphylococcus aureus ProRS (SaProRS)[1].
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Antibacterial agent 124 | Antibacterial agent 124 (Compound 3) is a potent bacterial prolyl-tRNA synthetase (ProRS) inhibitor with an IC50 of 0.18 μM against Staphylococcus aureus ProRS (SaProRS). | |||||||||||||||||||||
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