2304513-76-4
Chemical Structure
3-(6-Bromo-1-oxoisoindolin-2-yl)piperidine-2,6-dione
- CAS No.: 2304513-76-4
- Formula:C13H11BrN2O3
- Molecular Weight:323.15
IUPAC Name: 3-(6-bromo-1-oxoisoindolin-2-yl)piperidine-2,6-dione
InChIKey: FDMZEIZGNKTOII-UHFFFAOYSA-N
SMILES: O=C(C(N(CC1=C2C=C(Br)C=C1)C2=O)CC3)NC3=O
Biological Activity: 3-(6-Bromo-1-oxoisoindolin-2-yl)piperidine-2,6-dione is a Lenalidomide analog that can be useful in PROTAC research.
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3-(6-Bromo-1-oxoisoindolin-2-yl)piperidine-2,6-dione | 99.85% | 3-(6-Bromo-1-oxoisoindolin-2-yl)piperidine-2,6-dione is a Lenalidomide analog that can be useful in PROTAC research. | ||||||||||||||||||||
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Lenalidomide-6-F | 99.63% | Lenalidomide-6-F is the Lenalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein. Lenalidomide-6-F can be connected to the ligand for protein by a linker to form PROTAC. | ||||||||||||||||||||
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Lenalidomide-5-Br | 99.33% | Lenalidomide-5-Br is the Lenalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein. Lenalidomide-5-Br can be connected to the ligand for protein by a linker to form PROTAC. | ||||||||||||||||||||
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3-(6-Amino-1-oxoisoindolin-2-yl)piperidine-2,6-dione | 98.89% | 3-(6-Amino-1-oxoisoindolin-2-yl)piperidine-2,6-dione is a Lenalidomide analog that can be useful in PROTAC research because it is applicable to the recruitment of the CRBN protein. | ||||||||||||||||||||
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Desamino lenalidomide-6-OH | 99.36% | Desamino lenalidomide-6-OH is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. Desamino lenalidomide-6-OH can be linked to a target protein ligand via a linker to form a PROTAC. | ||||||||||||||||||||
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Desamino lenalidomide-6-I | ≥95.0% | Desamino lenalidomide-6-I is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. Desamino lenalidomide-6-I can be linked to a target protein ligand via a linker to form a PROTAC. | ||||||||||||||||||||
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(R)-Desamino lenalidomide-5-Br | 99.69% | (R)-Desamino lenalidomide-5-Br is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. (R)-Desamino lenalidomide-5-Br can be linked to a target protein ligand via a linker to form a PROTAC. | ||||||||||||||||||||
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Desamino lenalidomide-cyano | 99.91% | Desamino lenalidomide-cyano is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. Desamino lenalidomide-cyano can be linked to a target protein ligand via a linker to form a PROTAC. | ||||||||||||||||||||
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Desamino lenalidomide-5-CO | Desamino lenalidomide-5-CO is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. Desamino lenalidomide-5-CO can be linked to a target protein ligand via a linker to form a PROTAC. | |||||||||||||||||||||
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Desamino lenalidomide-6-propyne | 97.85% | Desamino lenalidomide-6-propyne is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. Desamino lenalidomide-6-propyne can be linked to a target protein ligand via a linker to form a PROTAC. | ||||||||||||||||||||
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(3S)Lenalidomide-5-Br | 98.61% | (3S)Lenalidomide-5-Br is a ligand for E3 ubiquitinase. (3S)Lenalidomide-5-Br can be used to synthesize PROTAC Cbl-b-IN-1 (HY-159608). | ||||||||||||||||||||
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