2313525-20-9
2313525-20-9
Chemical Structure
SET2
- CAS No.: 2313525-20-9
- Formula:C17H21F3N4O2S
- Molecular Weight:402.43
IUPAC Name: N-(furan-2-ylmethyl)-3-((4-(methyl(propyl)amino)-6-(trifluoromethyl)pyrimidin-2-yl)thio)propanamide
InChIKey: LZHSWRWIMQRTOP-UHFFFAOYSA-N
SMILES: O=C(CCSC1=NC(C(F)(F)F)=CC(N(CCC)C)=N1)NCC2=CC=CO2
Biological Activity: SET2 is a selective TRPV2 antagonist (IC50=0.46 μM). SET2 blocks the TRP channel and suppresses prostate cancer cells migration. SET2 reduces the lysophosphatidic acid (LPA, a TRPV2 activator)-induced cytoplasmic calcium increases[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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SET2 | 99.78% | SET2 is a selective TRPV2 antagonist (IC50=0.46 μM). SET2 blocks the TRP channel and suppresses prostate cancer cells migration. SET2 reduces the lysophosphatidic acid (LPA, a TRPV2 activator)-induced cytoplasmic calcium increases. | ||||||||||||||||||||
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